Biofreeze can aid in the treatment of injuries and chronic problems. Biofreeze can also be used in any situation requiring the use of ice or breathable wraps. It can effectively help relieve pain from sore muscles and muscle sprains, back, shoulder, neck pain, arthritis, painful ankle, knee, hip and elbow joints muscular strains and more.
We took the #1 clinically used and recommended topical analgesic and made it even better. An extensive study showed new and improved Biofreeze Pain Reliever is preferred by 4 out of 5 users.
The #1 clinical pain reliever now has an enhanced formulation in Green and new Colorless Biofreeze. Our two-plus years of testing and development confirm it is the best Biofreeze ever.
Biofreeze Pain Reliever delivers targeted pain relief with the benefits of cryotherapy to treat athletic and muscle related injuries, sore or strained muscles, shoulder and arm discomfort, neck, hip and leg pain, back pain, painful joints, ankle or foot pain, and pain associated with bruising, and arthritis.
• Applies easier and penetrates quickly
Mechanism of Action
Traditional thinking is that the pain-relieving mechanism of action of menthol - the active ingredient in Biofreeze Pain Reliever - results from a counter-irritant effect. Simply put, a counter-irritant has an effect of overriding noxious pain signals traveling to the brain through a process modulated between pain-transmitting and non-pain transmitting neurons. This process, known as "gate control" or "gating," was first described by Melzak and Wall.
Gate control theory is based on the understanding that pain is transmitted by two kinds of afferent nerve fibers. One is the larger myelinated A-delta fiber, which carries quick, intense-pain messages. The other is the smaller, unmyelinated "C" fiber, which transmits throbbing, chronic pain. A third type of nerve fiber, called A-beta, is "nonnociceptive," meaning it does not transmit pain stimuli. The gate control theory asserts that signals transmitted by the A-delta and C pain fibers can be thwarted by the activation/stimulation of the nonnociceptive A-beta fibers and thus inhibit an individual's perception of pain.
More recently, laboratory researchers have discovered that menthol stimulates the TRPM8 cold receptors. Even though it has long been accepted that cooling and cold can induce analgesia it has been a poorly understood mechanism. As scientists have continued to isolate these specific heat-sensitive transient receptor potential (TRP) channels within our sensory neurons we are now able to have a much better understanding of the body's cutaneous temperature detection. With the isolation and further study of these specific TRPM8 receptors there is stronger evidence supporting the benefits achieved with the cooling effect of menthol in functioning as a topical analgesic while activating these receptors and the resulting consequent pain relief.
• Enhanced and more natural formula
• Colorless (dye-free) options
• Proprietary herbal blend
• 100% paraben-free
• Effective skin conditioners
• Greaseless and non-staining with vanishing scent
• Manufactured in the USA
• Not tested on animals